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The chart below shows common female hormone patterns we see before, during, and after the menopause transition

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It improves microvascular perfusion, meaning better blood flow to painful areas, which can significantly reduce pain symptoms

17,18 Preclinical studies and veterinary use have suggested benefit in tendon and muscle repair, with observed anti-inflammatory effects and proangiogenic activity that mirror those of BPC-157

If you're taking progesterone as part of HRT, bedtime dosing is generally recommended because progesterone side effects can include sleepiness, dizziness, or grogginess in some women