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Safety: most dogs tolerate it well, but digestive upset can happen start low, give with food, and pause if anything seems off

Bensimon G, et al

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Glare sensitivity indicated mostly changes in lens clarity and confirmed the tiny changes in the optical media of the eye at the short-term follow up examinations when slit lamp associated image analysis data and densitometric readings did not differ significantly with baseline

Behavioral deficits have been reported in the offspring of rats given 0.5 times the MRHD on a mg/m2 basis throughout most of pregnancy