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In the production simulations, the particle mesh Ewald method 74 was used to treat long-range electrostatic interactions, and bonds involving hydrogen atoms were constrained using the SHAKE algorithm

Antioxidant responses The antioxidant responses, including the activities of hepatic enzymes superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx), were markedly improved in vitamin C-supplemented groups (Fig

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DIO2 is found in the pituitary gland, thyroid, and skeletal muscle