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Symptoms of Vitamin B12 Deficiency The human liver stores several years worth of vitamin B12, so having a deficiency isnt very common but lots of people have lower levels

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It remains questionable whether the development of hyperpigmentation is responsive to specific serum vitamin B12 levels [2]

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In difficult diagnostic cases of suspected vitamin B12 deficiency, when laboratory cobalamin test results do not correlate with clinical symptoms, it may be helpful to determine serum methylmalonic acid (MMA) or homocysteine levels [51,52,53]

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