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There are significant differences in the diffusion characteristics and mechanism of ROS produced by Type I and Type II PDT, which directly affect the design strategy and therapeutic effect of the prodrug system: Type I PDT generates OH through electron transfer reactions, which has extremely strong oxidizing ability but a very short lifetime, and its diffusion distance in the biological environment is short

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[DOI] [PubMed] [Google Scholar] 33.Lei Don, Yingjie Zhao, Cheng Su, Ziwei Ou Yang, Fan Chen, Weirong Hu