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The six-week period used seems to be suited for adequate model elaboration [11]

Monitoring during protocols Extended protocols warrant periodic assessment

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Likewise, the remaining serious pathology in the animals treated with L-NAME + L-arginine indicates that other system(s) ( i.e ., the BPC 157 system) may function along with the NO system, which was previously supposed to be inactivated by the combined action of L-NAME and L-arginine[3,52,53]