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The study established that AOD9604 mediates its fat-reducing effects through 3-AR upregulation and ACC inhibition, independent of the insulin-like growth factor (IGF-1) axis, which distinguishes its mechanism from full-length hGH

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These processes have been examined in cellular and animal models to characterize changes in metabolic efficiency and transcriptional signaling

Feb 2015;9(2):501-506

2016 Nov;101(11):3879-3883