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Full-length HGH has insulin-antagonistic effects that can raise blood glucose and reduce insulin sensitivity, potentially leading to insulin resistance with chronic use

Qiu Y, Ye X, Zhang HM, Hanson P, Zhao G, Tong L, Xie R, Yang D (2017) Cleavage of osmosensitive transcriptional factor NFAT5 by Coxsackieviral protease 2A promotes viral replication

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