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Akdis proposed an epithelial barrier hypothesis, suggesting that increased environmental toxicants and pollutants associated with industrialization, urbanization, and modern life lead to an increase in allergic, autoimmune, and chronic airway diseases by damaging epithelial barrier integrity (41)

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Bioconjugates of curcumin displayed improved neuroprotection activity (in terms of compensating the glutathione level) compared to curcumin [377]
