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Furthermore, coexpression of the egtA gene, which encodes -glutamylcysteine synthetase that synthesizes the -glutamylcysteine used as a sulfur source of ERG biosynthesis, enhanced ERG production even though E

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Studies have shown that phosphorylation of the E1 subunit by pyruvate dehydrogenase kinase (PDK) inhibits PDC activity, while dephosphorylation by pyruvate dehydrogenase phosphatase (PDP) activates the complex