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p53 enhances OXPHOS by inducing the expression of cytochrome c oxidase 2 (SCO2)

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Once at the IGF-1 receptor it triggers the same downstream anabolic cascade as IGF-1 PI3K/Akt and MAPK signaling that promotes protein synthesis and satellite-cell activity but its poor binding-protein affinity also means rapid clearance [3]
Conservative treatments include medications (e.g., steroids, vitamin B12, non-steroidal anti-inflammatory drugs [NSAID], and gabapentin), splint, and physiotherapy 4

Primary clinical applications at Balanced: gut healing (leaky gut, IBS, ulcers, GI inflammation peptide therapys original discovery context), tendon and ligament repair (accelerates healing of partial tears and chronic tendinopathy), joint health (supports cartilage repair and reduces joint inflammation), muscle injury recovery (faster return to function after strains and tears), post-surgical healing (accelerates tissue repair at surgical sites), and neuroprotection (supports nerve repair and reduces neuroinflammation)
