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Primary stimulation of O 2 by xanthine oxidase, O 2 dismutation, electron reduction at higher O 2 level are the main mechanisms of ROS generation in plants 60

Tomita K, Smith PM, Takayama M, Pan C, Shen S, Wang X, Wang XS, Williams LA, Arvide EM, To C, Rajaram R, Mitchell KG, Rice DC, Hofstetter W, Antonoff MB , Mehran RJ, Vaporciyan A, Walsh GL, Maxwell JE, Snyder RA, Kim MP, Tzeng CW, Mansfield PF, Swisher SS, Lee J, Badgwell BD, Katz M, Ikoma N

Zn can prevent apoptosis and thus prevent oxidative damage in the brain (Kocatrk et al., 1996)

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Science 200 , 5254 (1978)

Increased melanin production in the lips can lead to darkening, a condition often referred to as hyperpigmentation
