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Calculation of cholesterol saturation index (CSI) The CSI of bile was calculated using the method proposed by Carey et al

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Acetylation of histones: Acetylation and deacetylation of histones are crucial mechanisms for the regulation of the transcription

6 The reason for mitochondrial dysfunction in ASD is unknown, but the fact that only 23% of children with ASD and MD have a known mitochondrial deoxyribonucleic acid (mtDNA) abnormality suggests that MD may be acquired rather than genetic in many ASD cases

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