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Description
Continuous stimulation has been theorized to lead to receptor desensitization, whereas intermittent signaling may preserve responsiveness

It is known that such diseases include disorders of cardiovascular system (ischemic disorders, idiopathic hypertension), rheumatic diseases, chronic diseases of respiratory organs, ulcer, and skin diseases

Redox potential and peroxide reactivity of human peroxiredoxin 3

Collectively, MO could attenuate the negative impact of the chronic inflammation mainly through inhibiting the expression of a series of pro-inflammatory factors

Despite from that Nox4 does not require any further cytosolic subunit and therefore is constitutively active

doi: 10.1023/A:1022420007908
