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Kornblau SM, Estrov Z, Qui YH, Patel S, Kantarjian H, Beran M, Koller CA, Andreeff M

Vasileva SS

Epithalon and Improved Sleep Research interest in the effect of epithalon on sleep quality stems from the peptides ability to increase levels of melatonin, a hormone produced in the pineal gland that is critical to sleep quality

Trends Neurosci 35:373381

Smoldering disease activity This includes low-grade inflammation, mostly composed of activated infiltrating and CNS-resident myeloid cells, and neuronal deregulations that start early in the MS disease course and determine neurodegeneration and disability progression