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Terfenadine, a once popular antihistamine, was removed from the market because its metabolism was inhibited by CYP3A4 substrates such as erythromycin and grapefruit juice

Psychiatry 91 , 740752 (2022)

The reactive oxygen species (ROS) are short-lived oxygen derivatives that are unstable and highly reactive and formed as a byproduct of cellular metabolic processes

[DOI] [PubMed] [Google Scholar] 13.Sundaram RK, Bhaskar A, Vijayalingam S, Viswanathan M, Mohan R, Shanmugasundaram KR

& Bijad, E

Enroth C, Eger BT, Okamoto K, Nishino T, Pai EF (2000) Crystal structures of bovine milk xanthine dehydrogenase
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