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Whether cysteine S -conjugates, whose elimination products are very reactive, damage the gut and bile duct remains to be determined

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Indeed, upregulation of lactate, which may be present in the microenvironment as a consequence of increased glycolysis in cancer cells, has been shown to promote glutamine metabolism through a HIF2- and MYC-dependent mechanism, potentially providing a way for tumor to reprogramme itself towards increased glutaminolysis (8)

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Circadian rhythms in exudative age-related macular degeneration: the key role of the canonical WNT/-Catenin pathway