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Schmeisser K, Parker JA (2018) Nicotinamide- N -methyltransferase controls behavior, neurodegeneration and lifespan by regulating neuronal autophagy

There is also a practical argument for the stack

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For apical to basolateral (AB) and basolateral to apical (BA) permeability, compounds were added at 10 M concentration to the apical (A) side and basolateral (B) side, respectively, and the corresponding amount of permeation was determined by measuring compound concentration on the B or A side
Polysomnographic measurements confirmed shortened sleep onset latency, meaning participants fell asleep faster
