melanotic macule differential diagnosis macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight ⬆️ in single basal melanocytes; NO nests. More info like this in Oral pathology: Noting a pigmented
Description
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Vitiligo Repigmentation (Phase II Data) Afamelanotide has been studied as a combination therapy with narrowband UV-B (NB-UVB) phototherapy for nonsegmental vitiligo

The shine and color may fade away throughout the day, but the hydration won't

Jelinek, Arthur 1967 A Prehistoric Sequence in the Middle Pecos Valley New Mexico
