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Metabolites derived from the diet can interact with the intestinal epithelium causing stimuli that may directly induce structural damage in epithelial cells and activate pro-carcinogenic signalling pathways, or by indirectly interacting with the gut microbiota (14)

J Transl Med 23 , 530 (2025)

For example, adding B12 to other B vitamins helps those with complex nutritional deficiencies

Multiple reproductive abnormalities, including decreased oocyte maturation, disturbed follicular development and ovulation, heightened rates of follicular atresia, and eventually infertility, are caused by conditional deletion of Dicer1 exclusively in mammalian follicular granulosa cells (GCs) [87,88,89]

Athletes should consult their sport's governing body and anti-doping authority before considering any peptide supplement

however, larger studies are still needed to confirm these effects