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But does carnitine live up to the hype

In: StatPearls [Internet]

One suggested mechanism of carnitine action is its reduction of serum ammonia levels leading to improved psychometric measures [6365]

These effects were associated with decreased androgen receptors, mTOR and AKT expression signaling, and increased caspase-3 activation 35

The enrolled patients suffered from peripheral mono- and polyneuropathies of various origins including entrapment, traumatic, toxic/alcoholic, diabetic, metabolic, idiopathic, vascular or infective aetiology

In humans, administration of 2 g/day of ALCAR for 50 days increased plasma ALCAR concentrations by 43%, suggesting that either ALCAR was absorbed without prior hydrolysis or that L-carnitine was re-acetylated in the enterocytes (5)