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In these scenarios, redox signaling pathways do not regulate biomolecular and cellular activities through direct oxidative damage, but rather through redox modifications and the downstream signaling pathways they activate
Nat Food 2(1):1025 Quinn Z (2020) AI-driven resource management

The hemocompatibility of nanoparticles: A review of cellnanoparticle interactions and hemostasis

doi: 10.1093/cvr/cvaf068

(138) proved that paeoniflorin could significantly improve the symptoms of CIA rats, reduce the levels of pro-inflammatory factors (TNF-, IL-1 and IL-6), and down-regulate the expression of p-NF-B p65 and p-myosin-binding subunit (MYPT1)

There are no data on adverse effects of chronic high-dose GSH as used for skin lightening
