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Gastroenterology 159(4):14711486

535 Further studies revealed that the trimethylamine (TMA)/flavin-containing monooxygenase 3 (FMO3)/TMAO pathway is likely to regulate the cholesterol balance and inflammatory response via both the LXR and the FXR signaling pathways

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More specifically, this may be observed with respect to certain genes, including Egr, Nos, Srf, Vegr, Akt1, Plc , and Kras genes (Vukojevic et al., 2018), all of which are responsible for the synthesis of factors necessary for a diverse set of processes