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Recently, an emerging approach to inhibit overactive or overexpressed proteins is to develop proteolysis-targeting chimeras (PROTACs) that can efficiently degrade the targeted protein of interest (POI) by hijacking the ubiquitin-proteasome system 33,34
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The trapped ammonia was determined through titration with 0.1 N HCl and the burette reading was used to calculate the percentage of nitrogen using the formula - The percentage of nitrogen calculated was used for the calculation of total protein content using the conversion factor of 5.81
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Recent progress in mass spectrometry-based metabolomics in major depressive disorder research
