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In controlled studies, GHK-Cu has been shown to increase follicle size, extend the anagen (growth) phase, and improve overall hair density

Furthermore, this short-chain fatty acid regulates critical gastrointestinal functions by modulating epithelial cell proliferation, apoptosis, and differentiation in response to microbial growth and signaling mechanisms [10,34]

Simultaneously, the addition of probiotics and prebiotics (such as fructooligosaccharides, but not B-GOS) could reverse these changes (172, 173)

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Additionally, hormonal variations, particularly fluctuations in estrogen levels, have been shown to affect ligament laxity and strength, further contributing to the higher incidence of ACL injuries in females