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2 Historical and contemporary perspectives on honey in cancer care The use of honey for medicinal purposes is no less ancient than that of its consuming, it goes back to the times of Egyptian, Greek, Ayurvedic, and Chinese medicine ( 3 Chemical composition and therapeutic attributes of honey Most of the anticancer efficacy of honey is due to the rich profile of polyphenolic and flavonoid constituents, such as gallic acid, caffeic acid phenyl ester, chrysin, and quercetin, which act on oxidative stress, inflammatory pathways, and apoptotic signaling in cancerous cells

In other words, the equatorial conformer is more stable by 1.74 kcal/mol

Rus H, Cudrici C, Niculescu F

For example, in benzo[a]pyrene-exposed murine models, oral administration of curcumin at 60 mg/kg significantly attenuated ROS production and lipid peroxidation in pulmonary tissue, concomitant with restoration of intracellular glutathione (GSH) levels (Liu et al., 2015)