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Here is a general timeline of what to expect after glutathione injection: Within 2 weeks: A subtle glow and clearer, healthier-looking skin 3 to 4 weeks: Smoother skin texture and a more even complexion 1 to 3 months: Dark spots start to fade and overall dullness reduces 3 to 6 months: Noticeable brightening of skin with fewer blemishes Results can vary from person to person