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Karri V, Schuhmacher M, Kumar V

OS may disrupt neurotransmitter metabolism, such as that of serotonin (Ding et al., 2020), impair neurogenesis and synaptic plasticity (Hou et al., 2017), and induce DNA and RNA hypermethylation (Wu et al., 2021

[DOI] [PubMed] [Google Scholar] 85.Fromme H., Gareis M., Vlkel W., Gottschalk C

4 ChenD.GuoL.YiC.WangS.RuY.WangH

Following chronic liver injury, HSCs proliferate, lose their vitamin A and undergo a major phenotypical transformation to -smooth muscle actin (-SMA) positive activated HSCs, which produce a wide variety of collagenous and non-collagenous extracellular matrix (ECM) proteins [168]

Some gastrointestinal issues or loss of appetite may also benefit from a more stable metabolic rate