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Among these regulatory pairs, 3, 6, and 3 loci also displayed genetic colocalization effects in the three tissues, respectively (Fig

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Metabolic alterations and hepatitis C: from bench to bedside

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Overall, this study suggests caution in the use of MTAP status as the sole predictive biomarker for identifying patients to receive MAT2A/PRMT5 inhibitor therapy

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Swiderski MR, Birker D, Jones JD

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doi: 10.1038/ni.3578 179

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3OHK can also form 3-hydroxyanthranilic acid (3OAA), through the enzyme kynureninase (102)

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