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A prospective, placebo-controlled, randomized study (NCT00940602) found that DFX significantly reduced the combined risk of hospitalization for worsening heart function or congestive heart failure in MDS patients, but had no significant effect on left ventricular ejection fraction or pulmonary artery pressure

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Dopamine is the predominant catecholamine in mammalian brain and is involved in neurological functions such as locomotion, cognition, emotion and reward [15, 16]