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The high reactivity of GSH makes exact measurement of absolute concentrations challenging, likely leading to many discrepancies in reported concentrations in various biological systems

756,757 The combination of circular RNA Carm1 and miR-3098-3p regulates the expression of ACSL4 and has a protective effect on acute cerebral infarction injury

Many tumors depend on the availability of extracellular serine for rapid proliferation

Second, buffer proximity, as SODs, peroxiredoxins, GPx and local GSH pools are co-localized with ROS sources to sculpt H 2 O 2 lifetime and limit its reach and third, pulse design, since short, low-amplitude bursts favor selective thiol switches, whereas sustained or repeated pulses saturate these buffers and allow oxidants to spread to vulnerable macromolecules (Winterbourn 2020)

Marcel Dekker, Inc., New York, N.Y.;1992 33

10.1146/annurev.nu.14.070194.001245 Anderson JO, Warnick RE, Dalai RK: Replacing dietary methionine and cystine in chick diets with sulfate or other sulfur compounds