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Therefore, the above results suggested that ATF4 could suppress HuOCSC ferroptosis

VB12 In human metabolism, VB12 (cobalamin) plays a crucial role as a cofactor in the conversion of methylmalonyl-CoA to succinyl-CoA, which is essential for energy production [135]

Further dissection of the PIF4A fragment revealed no transactivation activity (Supplementary Fig

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HO-1 and the HO system in general are thought to play a critical role in cellular homeostasis where the presence of complementarity or overlap between the arms of action could result in some degree of redundancy that can help to ensure the induction of HO mediated critical effects