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Furthermore, GW501516 inhibited ERK1/2 phosphorylation, which is involved in serine STAT3 phosphorylation, and increased AMP-activated protein kinase (AMPK) phosphorylation, which can inhibit STAT3 phosphorylation

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doi: 10.1038/nm.3624 101 RobbaC.BattagliniD.BallL.PatronitiN.LoconteM.BrunettiI.et al

E3 enzyme ensures the specificity of the ubiquitination process by recognizing particular proteins [83]

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[DOI] [PubMed] [Google Scholar] Selen Alpergin et al