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Interestingly, it is shown that the mRNA levels of GLS and solute carrier family 1 member 5 (SLC1A5) increased in KRAS-driven NSCLC, suggesting that these cells are more dependent on glutamine rather than glucose metabolism (14)

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An under-researched area is the role of these transporters in the brainessential to understanding the influence of UA on neurodegenerative processeswhich will be discussed later in this article

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This study reported no difference in response to CCH therapy in the acute vs