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In cultured neurons, the replacement of glucose with BHB leads to changes in metabolic pathways, enhancing the TCA cycle flux, producing more -ketoglutarate, and ultimately converting to GABA in GABAergic neurons [38,195] (Figure 5A)

Diseases can occur when too many free radicals or enemies enter the body, and there is a lack of antioxidants or glutathione to fight them

Their incorporation in the nerve cell membranes of the brain occurs through developmental processes and contributes to the functional maturation of CNS

Additionally, approximately 30% of COVID-19 survivors develop COVID-associated pulmonary fibrosis (188, 190, 224)

Notes: Data are means SD

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