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This review attempts to summarize our current knowledge and updates on the mechanisms of NF-B pathway regulation and the potential therapeutic application of inhibition of NF-B signaling in cancer and inflammatory diseases.

Moreover, DHM decreased the levels of pyroptosis-related proteins, such as IL-18, NLRP3, ASC, GSDMD, and Caspase-1, and upregulated the levels of oxidative stress-related proteins, such as SOD1 and HO-1, in SCI mice

In experimental models, LC revealed neuroprotective effects, improving memory and reducing neuronal death

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