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ghk-cu tolerance or desensitization or loss of effectiveness or downregulation Tripeptide–copper complex GHK‐Cu (II) transiently improved healing outcome in a rat model ACL reconstruction - Fu - 2015 - Journal of Orthopaedic Research Peptide-Based Approaches for Pain Relief
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Steroid treatment can prevent your body producing enough natural steroids in response to a trauma such as an injury

doi:10.1016/bs.vh.2018.01.022 Hu Q, Zhang SY, Liu F, Zhang YL, Zhu DM, Zang YY

There are people that have a condition called albinism and they dont have the normal pigment in their skin or in their eyes

The copper peptides may actually buffer some of retinol's irritation potential while supporting the collagen-building effects both ingredients promote
Antimicrobial peptides (AMPs), which are widely found in the biological world, may help solve this problem

The Register of the Kentucky Historical Society, 123(3&4), 373-406
