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In renal lesions, IL-1 has been shown to induce alterations in renal tissue structure by modulating the proliferation of thylakoid cells and the synthesis of matrix, as well as by increasing vascular endothelial cell permeability

J Neurochem 95:919929

Although no negative situation has been observed regarding the use of curcumin during pregnancy and breastfeeding, it is not recommended for use by pregnant and lactating mothers due to the lack of sufficient scientific studies

A factor involved in breast tumour resistance to therapy over expression of the P-glycoprotein transporter, also appears to be present in human lung adenocarcinoma cell lines [216]