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Steroids are usually only used to treat the active disease because their long-term use is associated with a range of adverse side-effects

A serum B12 level test and, ideally, a methylmalonic acid (MMA) test should precede any B12 injection recommendation

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Further investigations targeting this disparity are warranted based on a study protocol designed to assess neurodegeneration and neuronal loss specifically in 5xFAD mice approaching one year of age [39]

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