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Other diagnostic tools, such as blood-based scores, often rely on indirect parameters, and liver imaging can be resource-intensive

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Some bacteria in our gut consume glycine, which is required for the synthesis of the glutathione, and imbalances in the composition of the bacteria may lead to the progression of the chronic diseases, says Chalmers researcher Adil Mardinoglu, first author of the paper

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Aberrant epigenetic changes can perturb key cellular processes, including cell cycle control, intercellular communication, DNA repair, inflammation, stress response, and apoptosis

Imbalance in mitochondrial fission and fusion is a key trigger for Parkinsons disease, and defects in mitochondrial dynamics limit mitochondrial movement, leading to a reduction in ATP, excessive oxidative stress, and mtDNA deficiency, which ultimately leads to cell death (Geng et al., 2019)