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It was documented that dietary supplementation containing vit B12 and folate, in a model of ischemic injury in mice, could improve the motor activity in the rotarod test (68)

Because the injections are given infrequently with a very small needle (typically a 25-gauge needle is adequate), this is not usually a very unpleasant experience for the cat

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The good news is that some people notice improvements within a few days, particularly if they have a significant deficiency

In fact, one study noted 1,0002,000 mg per day of NR caused no harmful effects in humans, aside from some mild side effects in a few participants