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At 3, 6, and 12-month follow-ups, the researchers found no significant difference in the outcomes or functional ability between the two groups

Moreover, treatment of CC mice with NA rescued NAD + levels in skeletal muscle, improved muscle function, and increased Oxphos complexes expression, yet NA treatment had no effect on mitochondrial respiration 248

Anti-inflammatory Mechanisms BPC-157 has been studied in models of inflammation, with research suggesting modulation of inflammatory cytokine activity

[DOI] [PubMed] [Google Scholar] 35.Current pharmaceutical treatments and alternative therapies of Parkinson's disease

Sunitinib Sunitinib (Sutent ) is a novel oral multitargeted TKI of VEGFR-1, VEGFR-2, fetal liver tyrosine kinase receptor 3, c-KIT, PDGFR-, and PDGFR- (Yardley et al., 2012)

[12] Considering all these data, we propose a hypothetical mechanism of crosstalk between muscle and other organs/tissues involving MOTS-c to explain our observation