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Applied geography 31 , 495507 (2011)

Proteases that promote ECM degradation, such as matrix metalloproteinases (MMPs), are considered enzymes that facilitate metastasis [104]

Bibcode:2009PNAS..106.6297L

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This is also reflected in a third anomaly: just above 0 C, water has a negative thermal expansion coefficient, indicating its increasing density with temperature

DG: Conceptualization, Data curation, Formal Analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing original draft, Writing review and editing