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Here, we identify FOXO4 as a pivot in senescent cell viability

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Inhibition of YAP/TAZ pathway contributes to the cytotoxicity of silibinin in MCF-7 and MDA-MB-231 human breast cancer cells

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Correspondingly, caspase-3 (pro-apoptotic proteins) activity in -viniferin-treated hepatocytes was measured at only 7.1% following 24 h exposure, compared with significantly higher activation in untreated or vincristine-only groups, demonstrating effective inhibition of the execution phase of apoptosis

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