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By comparing our in vitro predictive data to clinical liver toxicity monitoring in patients undergoing ribociclib treatment, we found that patient #2078 experienced grade 3 liver toxicity approximately 4 months after starting therapy, while patients #2080 and #2081 exhibited no hepatotoxic effects

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In the only human study, 11 of 12 patients receiving intra-articular BPC-157 injections reported significant knee pain improvement, with 7 maintaining relief over 6 months (Lee et al., 2021)

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Ther., 250: 149-153

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