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Editor: Oliver Chen, Tufts University, UNITED STATES Received: August 20, 2018

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Divergent sample preparation and analytical methods likely also contribute to the variable ergothioneine concentrations reported to date

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A glucosinolate metabolism pathway in living plant cells mediates broadspectrum antifungal defense

Unlike other forms of regulated cell death, cuproptosis is characterized by the direct binding of reduced copper (Cu + ) to lipoylated proteins of the tricarboxylic acid (TCA) cycle, most notably dihydrolipoamide S-acetyltransferase (DLAT), together with destabilization of iron-sulfur (Fe-S) cluster proteins such as succinate dehydrogenase complex ironsulfur subunit B (SDHB) 164