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Science 308, 648652

[DOI] [PubMed] [Google Scholar] Dowty ME, Lin J, Ryder TF, Wang W, Walker GS, Vaz A, Chan GL, Krishnaswami S, and Prakash C (2014) The pharmacokinetics, metabolism, and clearance mechanisms of tofacitinib, a janus kinase inhibitor, in humans
Consequently, the Trx and Grx systems maintain the balance of thiol-disulfide interactions in the reduction/oxidation conversion of protein forms, which act as target signaling pathways to regulate disulfide stress and may act as crucial triggers to suppress disulfidptosis

The reaction was monitored at 540 nm to specifically observe the impact that pH had on the rate of thiolate-FAD charge transfer formation for this variant
