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Vitamin B12 is water-soluble, meaning your body eliminates excess through urine rather than storing it to potentially toxic levels

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South Med J 1988

Its cellular-level mechanism appeals to those wanting to optimize metabolic function rather than override it

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Supplemental B12 favorably modulates persistently dysregulated inflammatory genes in the leukocytes of patients with VCD After 6 to 12 months from the initial diagnosis, CCL11 ( P = 0.0127) and LIF ( P = 0.0485) continued to show upregulation in leukocytes from individuals with persistent VCD compared to those from non-impaired subjects (Fig