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Pregnancy Reproductive studies have been performed in rats and rabbits at doses up to 3.8 times the human dose on the basis of surface area and have revealed no evidence of impaired fertility or harm to the fetus due to levocarnitine

Elevated acute phase reactant levels are associated with early synovitis and erosions as detected by magnetic resonance imaging, with inflammatory cellular infiltrates in synovium, and with osteoclastic activation and reduced bone mineral density

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