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Gogna, N., Krishna, M., Oommen, A

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doi: 10.1007/s00281-016-0574-0 29 SoldersMGorchsLGidlofSTibladELundellACKaipeH

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In a rat model of intervertebral disc degeneration, MOTS-c injection preserved disc height (82.4% versus 58.7% in the untreated group), restored MRI signals indicating improved disc hydration, and reduced histological degeneration scores by 44% compared to untreated controls

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IGFBP-3 is regulated mainly by GH but also to some degree by IGF-1

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Neuron 35 , 345353 (2002)

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